Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC750H1171N219O216S5

DescriptionStandard

        MAKVQFKPRATTEAIFVHCSATKPSQNIGVREIRQWHKEQGWLDVGYHFIIKRDGTVEAGRDELAVGSHVKGYNHNSVGVCLVGGIDDKGKFDANFTPAQMQALRSLLVTLLAKYEGSVLRAHHDVAPKACPSFDLNRWWEKNELVTSDRG
    

Molecular Weight16871.98 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.10

Net Charge (pH 7.4) 2.45

Charge Density (pH 7.0) 0.0205

GRAVY Index-0.40

Hydrophobic Moment 0.75

Boman Index-0.03

Instability Index35.14

Aliphatic Index 79.40

Aromaticity 0.0861

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7006.93

LogP -69.23

H-bond Donors 246.0

H-bond Acceptors 231.0

Rotatable Bonds 560.0

Heavy Atoms 1190.0

Ring Count 29.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130245 VERIFIED: NO

Provenance & Taxonomy

OrganismCitrobacter phage phiCFP-1 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic