Peptide Database

Peptide NameSLAY-screened peptide P1086

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC66H98N16O20

DescriptionStandard

        GLPYDLPDVPNVH
    

Molecular Weight1435.58 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-2.15

Net Charge (pH 7.4) -2.41

Charge Density (pH 7.0) -0.1655

GRAVY Index-0.32

Hydrophobic Moment 0.33

Boman Index0.18

Instability Index66.09

Aliphatic Index 104.62

Aromaticity 0.0769

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 552.75

LogP -3.49

H-bond Donors 16.0

H-bond Acceptors 19.0

Rotatable Bonds 38.0

Heavy Atoms 102.0

Ring Count 5.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0186000 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/