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MYP_033292
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Basic Information
1039
Antimicrobial
Immunology ▸ Chemokine signaling ▸ Chemokine-inducing activity
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Standard
9 amino acids
C62H98N20O10
Standard
Sequence
IWVIRRVWR
Physicochemical Analysis
1283.57 Da
12.00
2.76
2.56
0.3067
0.23
0.86
-0.12
63.10
151.11
0.2222
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
513.40
-0.08
21.0
13.0
39.0
92.0
4.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0433443 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Chemokine-inducing
human peripheral blood mononuclear cells (PBMC); Gro-α (CXCL1)
1717 pg/mL
chemokine induction assay (capture ELISA; peptide 100 μg/mL)
PaperUS9017656B2, Example 8 / Table 11: chemokine induction in human PBMC by peptide 1039 (IWVIRRVWR). PatentUS9017656B2
RECORD: Rec_0433480 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Innate defense regulator / cationic host-defense peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Chemokine-inducing
human peripheral blood mononuclear cells (PBMC)
13 pg/mL
MCP-3 chemokine induction by capture ELISA
PaperPatent US 9017656 B2, Table 11 PatentUS 9017656 B2
RECORD: Rec_0433481 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Innate defense regulator / cationic host-defense peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Chemokine-inducing
human peripheral blood mononuclear cells (PBMC)
67 pg/mL
MCP-3 chemokine induction by capture ELISA
PaperPatent US 9017656 B2, Table 11 PatentUS 9017656 B2
RECORD: Rec_0433482 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Innate defense regulator / cationic host-defense peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Chemokine-inducing
human peripheral blood mononuclear cells (PBMC)
469 pg/mL
Gro-α chemokine induction by capture ELISA
PaperPatent US 9017656 B2, Table 11 PatentUS 9017656 B2
RECORD: Rec_0433483 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Innate defense regulator / cationic host-defense peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Chemokine-inducing
human peripheral blood mononuclear cells (PBMC)
1717 pg/mL
Gro-α chemokine induction by capture ELISA
PaperPatent US 9017656 B2, Table 11 PatentUS 9017656 B2
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