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MYP_033280
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Basic Information
Scapularisin-6
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
38 amino acids
C176H260N58O50S6
Standard
Sequence
GFGCPFDQGACHRHCQSIGRRGGYCAGFIKQTCTCYHN
Physicochemical Analysis
4180.70 Da
8.68
2.96
2.51
0.0779
-0.47
0.72
-0.04
91.57
25.79
0.1316
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1739.80
-22.69
67.0
62.0
132.0
290.0
9.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0031518 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Listeria grayi DSM 20601
120 μM
MIC
PMID25443032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25443032/
RECORD: Rec_0037140 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0050558 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
F. culmorum
PaperDefensins from the tick Ixodes scapularis are effective against phytopathogenic fungi and the human bacterial pathogen Listeria grayi.
RECORD: Rec_0052260 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0068290 VERIFIED: YES
Provenance & Taxonomy
Ixodes scapularis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis DSM 3269
PMID25443032 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25443032/
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