Peptide Database

Peptide NameAngiotensin II

Function Ontology

Annotation / Sequence feature ▸ Secretory pathway ▸ Secreted protein

Cardiovascular

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC44H60N12O11

DescriptionStandard

        DRVYHPF
    

Molecular Weight933.02 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0218

GRAVY Index-1.01

Hydrophobic Moment 0.70

Boman Index-0.17

Instability Index28.06

Aliphatic Index 41.43

Aromaticity 0.2857

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 377.24

LogP -1.64

H-bond Donors 13.0

H-bond Acceptors 12.0

Rotatable Bonds 25.0

Heavy Atoms 67.0

Ring Count 4.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267434 VERIFIED: YES

Provenance & Taxonomy

OrganismUnknown [Animal]

FamilyAngiotensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cardiovascular

Half-LifeMammalian: 1.1 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0336329 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilySerpin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Secreted protein

RECORD: Rec_0404616 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/