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MYP_033260
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Basic Information
Cordyheptapeptide C
Anticancer
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
not Standard
7 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XFXPXLV
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0113372 VERIFIED: YES
Provenance & Taxonomy
Acremonium persicinum SCSIO 115 [Fungus]
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
SF-268 cells
3.7 μM
IC50 (cytotoxicity assay)
PaperChen Z et al. Cyclic heptapeptides, cordyheptapeptides C-E, from the marine-derived fungus Acremonium persicinum SCSIO 115 and their cytotoxic activities. J Nat Prod. 2012;75(6):1215-1219. DOI:10.1021/np300152d. PMID:22642609. PMID22642609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22642609/
RECORD: Rec_0298905 VERIFIED: YES
Provenance & Taxonomy
Acremonium persicinum SCSIO 115 [Fungus]
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic Cytotoxic
MCF-7 cells
3.0 μM
IC50 (cytotoxicity assay)
PaperChen Z et al. Cyclic heptapeptides, cordyheptapeptides C-E, from the marine-derived fungus Acremonium persicinum SCSIO 115 and their cytotoxic activities. J Nat Prod. 2012;75(6):1215-1219. DOI:10.1021/np300152d. PMID:22642609. PMID22642609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22642609/
RECORD: Rec_0328994 VERIFIED: YES
Provenance & Taxonomy
Acremonium persicinum SCSIO 115 [Fungus]
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
SF-268 cells
3.7 μM
IC50
PaperChen Z et al. Cyclic heptapeptides, cordyheptapeptides C-E, from the marine-derived fungus Acremonium persicinum SCSIO 115 and their cytotoxic activities. J Nat Prod. 2012;75(6):1215-1219. DOI:10.1021/np300152d. PMID:22642609. PMID22642609 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22642609/
RECORD: Rec_0433478 VERIFIED: YES
Provenance & Taxonomy
Acremonium persicinum SCSIO 115 [Fungus]
cyclic heptapeptide
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Anticancer Cytotoxic
MCF-7 cells
3.0 μM
IC50
PaperCyclic Heptapeptides, Cordyheptapeptides C-E, from the Marine-Derived Fungus Acremonium persicinum SCSIO 115 and Their Cytotoxic Activities PMID22642609
RECORD: Rec_0433479 VERIFIED: YES
Provenance & Taxonomy
Acremonium persicinum SCSIO 115 [Fungus]
cyclic heptapeptide
Structure & Mods
cyclic peptide [Cyclic]
noncanonical stereochemical modification [Modified]
Bio-Activity Profile
Anticancer Cytotoxic
NCI-H460 cells
11.6 μM
IC50
PaperCyclic Heptapeptides, Cordyheptapeptides C-E, from the Marine-Derived Fungus Acremonium persicinum SCSIO 115 and Their Cytotoxic Activities PMID22642609