Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length441 amino acids

Chemical FormulaC2213H3583N571O632S16

DescriptionStandard

        MKSCVVIFFLVSLISSDTAAPPPGIKVRITEKVKDLGLMYLKGLVNREFLIENEDFLIKSVTLTKLQIDPAQVDFRFQDKIGLQFEIRDLNFALQLQREKNVQFFKKFKIDKGTTIFTGEGVRAMILVRMNQNPKGHLNVEIGKEDCKINADSIRTKSTGFVGKVLDKFKSLTKHFFKKKICPALQPMINDKLKDLSTMRTVHEGRQLDLDYSLSSDIAVTSRSLDMSFKGLMSVRGQAVDTDSIRPGKEPVFTETNKMIYVGISEFFFNGAAMAIYKSGPFEVNVPKLEGLKSVVNLLLGAVGIQPGLLKVKLTKAPIIQISKAGLSATVDIETQSEGQQSVLVSCKLDMNVKFEASRLIPVIKTPKCNVETQKIIGKIVVGAAKAILYFVDKWFDEGIPIPLPTDLSFIDAKTQFEEGYLVVGGSLNFIPLQSSSNAGG
    

Molecular Weight48813.61 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)11.75

Net Charge (pH 7.4) 11.18

Charge Density (pH 7.0) 0.0266

GRAVY Index0.02

Hydrophobic Moment 0.63

Boman Index0.08

Instability Index24.65

Aliphatic Index 100.95

Aromaticity 0.0794

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14690.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141546 VERIFIED: NO

Provenance & Taxonomy

OrganismOreochromis niloticus (Not founde tilapia) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria