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MYP_033228
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Basic Information
H4-(86-100) (histone-derived)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
15 amino acids
C82H129N23O20
Standard
Sequence
VVYALKRNGRTLYGF
Physicochemical Analysis
1757.04 Da
10.28
2.73
2.52
0.1821
0.01
0.63
0.01
28.71
97.33
0.2000
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
724.32
-5.08
27.0
23.0
56.0
125.0
3.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042672 VERIFIED: YES
Provenance & Taxonomy
rat [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial
Active against E
PMID18803668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803668/
RECORD: Rec_0072877 VERIFIED: YES
Provenance & Taxonomy
Rattus norvegicus [Animal]
Defensin
10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID18803668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803668/
RECORD: Rec_0205718 VERIFIED: YES
Provenance & Taxonomy
rat [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial
PMID18803668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803668/
RECORD: Rec_0208905 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli (LD90 6.68 ug/ml), Pseudomonas aeruginosa (LD90 4.8 ug/ml), Bacillus subtilis (LD90 17 ug/ml)
PaperAntimicrobial effects of H4-(86-100), histogranin and related compounds--possible involvement of DNA gyrase.
RECORD: Rec_0213601 VERIFIED: YES
Provenance & Taxonomy
rat [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis
17 μg/mL
LD90
PMID18803668 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803668/
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