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MYP_033211
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Basic Information
P3
Antimicrobial
Antiviral
Antiviral ▸ Anti-Flavivirus ▸ Anti-Japanese encephalitis virus
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Standard
12 amino acids
C64H95N19O20
Standard
Sequence
SENRKVPFYSHS
Physicochemical Analysis
1450.55 Da
8.33
0.55
0.29
0.0457
-1.41
0.19
-0.32
77.41
24.17
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
652.54
-7.84
23.0
22.0
45.0
103.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0210468 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-JEV Fusion inhibition
Japanese encephalitis virus (JEV) | BHK-21 cells
100 μM
IC90
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitor of Japanese encephalitis virus infection targeting envelope protein domain III. | Zu X, Liu Y, Wang S, Jin R, Zhou Z, Liu H, Gong R, Xiao G, Wang W. | Antiviral Res. 2014 Apr;104:7-14. | DOI:10.1016/j.antiviral.2014.01.011 | PMID:24468276 PMID24468276 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24468276/
RECORD: Rec_0264740 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-JEV Fusion inhibition
Japanese encephalitis virus (JEV) | BHK-21 cells
1.12±0.38 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitor of Japanese encephalitis virus infection targeting envelope protein domain III. | Zu X, Liu Y, Wang S, Jin R, Zhou Z, Liu H, Gong R, Xiao G, Wang W. | Antiviral Res. 2014 Apr;104:7-14. | DOI:10.1016/j.antiviral.2014.01.011 | PMID:24468276 PMID24468276 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24468276/
RECORD: Rec_0271532 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-JEV Fusion inhibition
Japanese encephalitis virus (JEV) | BHK-21 cells
1.42±0.41 μM
IC50
Mammalian: 1.9 h; Yeast: >20 h; E. coli: >10 h
PaperPeptide inhibitor of Japanese encephalitis virus infection targeting envelope protein domain III. | Zu X, Liu Y, Wang S, Jin R, Zhou Z, Liu H, Gong R, Xiao G, Wang W. | Antiviral Res. 2014 Apr;104:7-14. | DOI:10.1016/j.antiviral.2014.01.011 | PMID:24468276 PMID24468276 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24468276/
RECORD: Rec_0398284 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Japanese encephalitis virus (JEV):inhibition of JEV infection in BHK-21 cells
1.42±0.41 μM
IC50
PMID24468276 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24468276/