Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length637 amino acids

Chemical FormulaC3054H4918N840O931S14

DescriptionStandard

        MTTPAYYINGVPYEASGQVIITITNGPTSPVGNVGNSPIAPLPVYVPWQQTHGGGSIAYDPNKVVFYGLSALRDTQTKINQILALARNAYPQNAEQIRDEANALLADLITGLINHPEINTLTRALQDAINSLQINIDLKNQQERIVSIRVQETEVAFRDFMNNNKMSNFIDKSAGMIDVAISTTGPWFIDLWNKAVPPKINAEIEAKNKLVTYLDWVKTVKEDVSSKKNTLIEIKNRVEADAAAKAKAEVEARAKAEAEARAKLAALMLVAGVNPTPVYTSEMVKSAQSALTAAGRMILNRASGMLQLSTIAEGILTTTSEGAGTIAGALWRGAMELSRIATVSAVGSTVCALVVGFYPKKVGEGSDKVPGRDIEMFAAQAQLFAAGKVNIQPEMTSVNLPVRGLLVTENGRQYVSLVKTGVNGVSANVPVLRAVRDEKTGLDKITLPAVGGVPARTILINPVPTGPAAPPHTGNSSPVPVTPVHTGTEIKQVASIVTTTYPADDLQGLQDFIYWQPDAAGTGVEPIYVMLSEPLDSGRFTRKQLDKKFKHAIDFGINDTKKNSETLTKYRDAIEAHLADTGTVERGTYRREKGSRVYFNPKTMNVVILKADEKFLSGWKINPDADNGRIYLETGDL
    

Molecular Weight68747.70 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)2.09

Net Charge (pH 7.4) 1.39

Charge Density (pH 7.0) 0.0033

GRAVY Index-0.16

Hydrophobic Moment 0.72

Boman Index0.06

Instability Index32.85

Aliphatic Index 92.81

Aromaticity 0.0612

Extinction Coeff. Reduced 65320.00

Extinction Coeff. Oxidized 65320.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420309 VERIFIED: YES

Provenance & Taxonomy

OrganismEnterobacterales bacterium 8AC [Bacterium]

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli