Peptide Database

Peptide NameProgonadoliberin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC355H560N100O106S

DescriptionStandard

        QHWSFGLSPGGKRELKYFPNTLENQIRLLNSNTPCSDLSHLEESSLAKIYRIKGLLGSVTEAKNGYRTYK
    

Molecular Weight7956.92 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)3.93

Net Charge (pH 7.4) 3.59

Charge Density (pH 7.0) 0.0561

GRAVY Index-0.69

Hydrophobic Moment 0.65

Boman Index-0.10

Instability Index17.76

Aliphatic Index 79.43

Aromaticity 0.1000

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3370.83

LogP -35.69

H-bond Donors 119.0

H-bond Acceptors 113.0

Rotatable Bonds 267.0

Heavy Atoms 562.0

Ring Count 13.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0173427 VERIFIED: YES

Provenance & Taxonomy

OrganismOryzias latipes [Animal]

FamilyProgonadoliberin

Tax ID8090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour