Peptide Database

Peptide NameHepcidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC450H707N127O125S12

DescriptionStandard

        RIVLWKVFSVAVTVAVVVVCICIHESTAVPFSEVRPEEAGNIHNPVGDMQQPGGESMNLPPFNFRIKRQSHLSLCRYCCACCYNKGCGFCCKS
    

Molecular Weight10280.98 Da

Isoelectric Point (pI)8.39

Net Charge (pH 7.0)2.93

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0315

GRAVY Index0.22

Hydrophobic Moment 0.45

Boman Index0.11

Instability Index60.74

Aliphatic Index 80.54

Aromaticity 0.0860

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 9105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3994.24

LogP -39.74

H-bond Donors 146.0

H-bond Acceptors 143.0

Rotatable Bonds 328.0

Heavy Atoms 714.0

Ring Count 18.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031891 VERIFIED: NO

Provenance & Taxonomy

OrganismEsox lucius [Bacterium]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal