Peptide Database

Peptide NameSLAY-screened peptide P5796

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC69H124N20O23

DescriptionStandard

        SLSILRDELVTRVT
    

Molecular Weight1601.84 Da

Isoelectric Point (pI)5.79

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0383

GRAVY Index0.38

Hydrophobic Moment 0.21

Boman Index-0.03

Instability Index24.67

Aliphatic Index 152.86

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 720.94

LogP -7.19

H-bond Donors 27.0

H-bond Acceptors 23.0

Rotatable Bonds 54.0

Heavy Atoms 112.0

Ring Count 0.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229457 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/