Peptide Database

Peptide NameTp0451a_N

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC149H223N53O46S6

DescriptionStandard

        GCGSHCNCNVGYHRSLHCYGNELHGKQCGFSRCG
    

Molecular Weight3685.08 Da

Isoelectric Point (pI)8.34

Net Charge (pH 7.0)2.05

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.0603

GRAVY Index-0.63

Hydrophobic Moment 0.54

Boman Index-0.08

Instability Index20.28

Aliphatic Index 31.47

Aromaticity 0.0882

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1598.97

LogP -23.47

H-bond Donors 62.0

H-bond Acceptors 58.0

Rotatable Bonds 119.0

Heavy Atoms 254.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395911 VERIFIED: YES

Provenance & Taxonomy

OrganismTreponema pallidum [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

TargetM. smegmatis MC 1553355 (MIC 34.7 ?9.5 uM)