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MYP_033042
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Basic Information
fTat
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
11 amino acids
C64H118N32O14
Standard
Sequence
YGRKKRRQRRR
Physicochemical Analysis
1559.83 Da
12.00
7.76
7.55
0.7052
-3.64
0.49
-1.66
204.74
0.00
0.0909
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
841.08
-10.07
34.0
22.0
58.0
110.0
1.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0358053 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Histidine tagged
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23454269 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23454269/
RECORD: Rec_0369251 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 36.4%, E 0.0%, T 36.4%, C 27.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antimicrobial
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0377469 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID22452378 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22452378/
RECORD: Rec_0380753 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral Anti-Gram-negative
Staphylococcus aureus
1.5-3.1 μM
MIC
PMID33892275 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33892275/
RECORD: Rec_0402094 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperDesigned cell penetrating peptide dendrimers efficiently internalize cargo into cells PMID24870379 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24870379/
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