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MYP_033042
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Basic Information
fTat
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antiviral
Antiviral ▸ Anti-Herpesvirus ▸ Anti-HSV
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
11 amino acids
C64H118N32O14
Standard
Sequence
YGRKKRRQRRR
Physicochemical Analysis
1559.83 Da
12.00
7.76
7.55
0.7052
-3.64
0.49
-1.66
204.74
0.00
0.0909
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
841.08
-10.07
34.0
22.0
58.0
110.0
1.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0213499 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
Conjugation with substrate
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23621550 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23621550/
RECORD: Rec_0232542 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Bio-Activity Profile
-
RECORD: Rec_0268911 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-penetrating peptide
HPLC
Human plasma, in vitro; >24000 s
PMID19601640 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19601640/
RECORD: Rec_0274606 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Conjugation with reverse sequence of CBD3 peptide of CRMP2
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23106100 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23106100/
RECORD: Rec_0299336 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
Tat
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorophore labeling
None
N-term detail: Texas red
Bio-Activity Profile
Cell-penetrating peptide
HeLa; TM12 cells
Fluorescence-based uptake assay
PMID12417587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12417587/
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