Peptide Database

Peptide NameDefensin alpha 6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length100 amino acids

Chemical FormulaC471H741N135O157S8

DescriptionStandard

        MRTLIFLAAILLVALQAQAEPLQAEDEPLQTSAYEADAQEQRGEDNQDFTISFAGDANSRIRALGSTRSFTCNCRRSCYSTEYSYGTCTVMGVSNRFCCL
    

Molecular Weight11063.25 Da

Isoelectric Point (pI)4.61

Net Charge (pH 7.0)-4.54

Net Charge (pH 7.4) -4.86

Charge Density (pH 7.0) -0.0454

GRAVY Index-0.20

Hydrophobic Moment 0.57

Boman Index-0.03

Instability Index54.45

Aliphatic Index 71.40

Aromaticity 0.0900

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4768.26

LogP -58.67

H-bond Donors 173.0

H-bond Acceptors 161.0

Rotatable Bonds 365.0

Heavy Atoms 771.0

Ring Count 11.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248314 VERIFIED: NO

Provenance & Taxonomy

OrganismCercocebus atys [Animal]

FamilyDefensin

Tax ID9531

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence