MYP_032971
Basic Information
KK15
Neurological / Signaling Analgesic/opioid activity Analgesic
Standard
13 amino acids
C66H106N22O21
Standard
Sequence
ELYENKPNARGRP
Physicochemical Analysis
1543.68 Da
8.69
0.84
0.66
0.0644
-2.02
0.14
-0.53
24.13
37.69
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
725.77
-7.99
24.0
22.0
49.0
109.0
3.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0245459 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
9913
Structure & Mods
linear peptide [Linear]
modified L-amino-acid analogue [Modified]
None
None
N3-L-Arg at 8th arginine position
Bio-Activity Profile
Neurotensin analogue Receptor ligand Serum-stable peptide
rat serum proteases
174±7 min
MALDI-TOF-MS serum stability half-life
Rat serum, in vitro; 10440 s
RECORD: Rec_0433413 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Structure & Mods
linear peptide [Linear]
modified L-amino-acid analogue [Modified]
N3-L-Arg at 8th arginine position
Bio-Activity Profile
Protease stability
Rat serum proteases
174±7 minute
MALDI-TOF-MS
RECORD: Rec_0433418 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
N3-L-Arg at 8th arginine position
Bio-Activity Profile
Neurotensin analogue Receptor ligand
human neurotensin receptor 1 (NTS1)
0.400 nM
IC50 receptor binding
RECORD: Rec_0433419 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
N3-L-Arg at 8th arginine position
Bio-Activity Profile
Neurotensin analogue Receptor ligand
human neurotensin receptor 2 (NTS2)
0.900 nM
IC50 receptor binding