Peptide Database

Peptide NameCompond 6 (ABT-510)

Function Ontology

Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC36H64N12O14

DescriptionStandard

        SARGVITDA
    

Molecular Weight888.97 Da

Isoelectric Point (pI)5.55

Net Charge (pH 7.0)-0.54

Net Charge (pH 7.4) -0.75

Charge Density (pH 7.0) -0.0599

GRAVY Index0.27

Hydrophobic Moment 0.43

Boman Index0.06

Instability Index-0.54

Aliphatic Index 97.78

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 435.78

LogP -6.24

H-bond Donors 16.0

H-bond Acceptors 14.0

Rotatable Bonds 28.0

Heavy Atoms 62.0

Ring Count 0.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236759 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermAcetylation

C-TermN-Ethylmaleimidation

Other Mods4th AA is D isoform of allo- Ile, Sar- Sarcosine

Bio-Activity Profile

Function

Anti-angiogenic

Activity0.00089±2.9e-05 μM

MethodIC50

Half-LifeMonkey plasma, in vivo; 4320 s