Peptide Database

Peptide NameInsulin B chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC148H220N42O40S2

DescriptionStandard

        VGGPQHLCGSHLVDALYLVCGDRGFFYNPR
    

Molecular Weight3291.72 Da

Isoelectric Point (pI)6.87

Net Charge (pH 7.0)-0.11

Net Charge (pH 7.4) -0.46

Charge Density (pH 7.0) -0.0037

GRAVY Index0.07

Hydrophobic Moment 0.45

Boman Index0.16

Instability Index14.41

Aliphatic Index 84.33

Aromaticity 0.1333

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1292.27

LogP -11.42

H-bond Donors 46.0

H-bond Acceptors 44.0

Rotatable Bonds 100.0

Heavy Atoms 232.0

Ring Count 8.0

Amide Bonds 31.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0136197 VERIFIED: YES

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyInsulin

Tax ID8128

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0271743 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0334444 VERIFIED: YES

Provenance & Taxonomy

OrganismOreochromis niloticus [Animal]

FamilyInsulin

Tax ID8128

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 100 hour; Yeast: >20 hour; E. coli: >10 hour