Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length401 amino acids

Chemical FormulaC2010H3212N516O595S12

DescriptionStandard

        MMLARPYCAVVVLLLLAGVSRTGEGNSNPGFMARITKKGLEYVQQYVVTTLKEQLSTIRLPDLSGHSKIDLIGWVSYDFHSLKIHRFVLQNWNLNLLPELGIGVFLSNSYMSVGGDWKVNKAFITLDGSFELKANGISISLSLNLDKDQSGRPTASVTECSNSIGHISIHLSGSLSWILNLFHEIIENNIKMVLEEKVCDMVTEFTTSYLELYLRTLPVTTMIDEVASLDYRLVGAPQVTSEGLDIPFKLARLYPNMEVELEVSLESEPLLTLTPGNVTLSPVIDIRGLALLPSSSDQRTLFQLRVNTNVSIAIGVNSNRIVGSVTIGSELKFEVKQSNLGNINKKLMESIFSYYTIKTIYSSLNAKLQEGFPLPLPRETSLNSVELQIHKNLLFVGAYFD
    

Molecular Weight44510.88 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-5.86

Net Charge (pH 7.4) -6.58

Charge Density (pH 7.0) -0.0146

GRAVY Index0.13

Hydrophobic Moment 0.71

Boman Index0.14

Instability Index36.79

Aliphatic Index 112.22

Aromaticity 0.0798

Extinction Coeff. Reduced 41370.00

Extinction Coeff. Oxidized 41495.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085457 VERIFIED: NO

Provenance & Taxonomy

OrganismOctodon degus (Degu) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria