Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2324H3808N642O649S21

DescriptionStandard

        MSLFSWIIVVLLIATTSGVNPGVKVRLTAKGLEYGRQVGMAAIQQNLRTIKIPDISGKKRISRIGKVKYRLSNGSCPGDWFFQNNVILSPHRRKSGSFDLNVDRLGVSANIAIKSDSTGRPVVSTPSCSASVGSVRVKFRGGASWLYNLFNKFINKALRKAMQKQICPLVSRAISGVNPQLQTLNVLAKVDKLAEIDYSMTSSPTISKSSIDLNMKGEFYNIGRHQEPPFSPAAFSLPPQVNKMAYIGMSAFTANSAGFVYNRAGILTLNITDDMIPKSSPIRLNTRALGTFIPEIARRFPGLLVKMVVKTAKPPVITFQPNNATVQTIGTITAFAIQRNTTLSPLFVLNIDTSVSAKLSINGMKVVGKVSLNRLDLTMGTSSVGQFQVRALDNILEIVLRAVIIPLVNVKLSGGYPLPATGKMKLMNTDLQILKVRDDILCITRYMCWIYYITGILMRPEQSTQNIIVRMK
    

Molecular Weight51800.37 Da

Isoelectric Point (pI)10.38

Net Charge (pH 7.0)35.62

Net Charge (pH 7.4) 35.14

Charge Density (pH 7.0) 0.0755

GRAVY Index0.11

Hydrophobic Moment 0.83

Boman Index0.09

Instability Index44.11

Aliphatic Index 103.03

Aromaticity 0.0699

Extinction Coeff. Reduced 38390.00

Extinction Coeff. Oxidized 38640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0036146 VERIFIED: NO

Provenance & Taxonomy

OrganismEcheneis naucrates [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria