Peptide Database

Peptide NameSLAY-screened peptide P3630

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC57H93N19O15S

DescriptionStandard

        RRTCVPVYHVS
    

Molecular Weight1316.53 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)1.84

Net Charge (pH 7.4) 1.57

Charge Density (pH 7.0) 0.1669

GRAVY Index-0.14

Hydrophobic Moment 0.38

Boman Index-0.16

Instability Index93.69

Aliphatic Index 79.09

Aromaticity 0.0909

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 558.70

LogP -5.54

H-bond Donors 22.0

H-bond Acceptors 19.0

Rotatable Bonds 38.0

Heavy Atoms 92.0

Ring Count 3.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0413984 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/