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MYP_032863
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C29H37N5O7
Standard
Sequence
WYSL
Physicochemical Analysis
567.63 Da
5.52
-0.24
-0.45
-0.0602
0.20
0.40
0.49
7.50
97.50
0.5000
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
206.87
0.56
8.0
7.0
14.0
41.0
3.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0025729 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
4.04 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0038807 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperHernandez-Ledesma B., Amigo L., Recio I., Bartolome B.. ACE-inhibitory and radicalscavenging activity of peptides derived from beta-lactoglobulin f(19-25). Interactions with ascorbic acid. J. Agric. Food Chem., 55 (2007), 3392-3397.
RECORD: Rec_0107317 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
90.4
IC50
PaperHernandez-Ledesma B., Amigo L., Recio I., Bartolome B.. ACE-inhibitory and radical scavenging activity of peptides derived from beta-lactoglobulin f(19-25). Interactions with ascorbic acid. J. Agric. Food Chem., 55 (2007), 3392-3397.
RECORD: Rec_0156883 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Anti-inflammatory Macrophage-modulating
Macrophages
PaperIsolation and characterization of anti-inflammatory peptides derived from whey protein | Ma, Y. et al. | DOI: 10.3168/jds.2016-11186 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0240261 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
90.4 μM
IC50
PaperACE-Inhibitory and Radical-Scavenging Activity of Peptides Derived from β-Lactoglobulin f(19-25) Interactions with Ascorbic Acid | Hernandez-Ledesma, B. et al. | DOI: 10.1021/jf063427j Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
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