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MYP_032846
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Basic Information
Scolopendin 1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
48 amino acids
C233H387N63O73S
Standard
Sequence
MDSFQKIEKIGEGTYGVVYKAKDKVSGRLVALKKIRLENESEGVPSTA
Physicochemical Analysis
5271.01 Da
9.10
1.51
1.27
0.0314
-0.47
0.63
-0.08
21.72
85.21
0.0625
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2237.29
-22.07
78.0
76.0
186.0
370.0
4.0
49.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0300347 VERIFIED: YES
Provenance & Taxonomy
Chinese red-headed centipede [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal
fungi Candida albicans ATCC 90028, C. parapsilosis ATCC 22019, and T. beigelii KCTC 7707
10-20 μM
MIC
PaperIdentification of a novel antimicrobial peptide, scolopendin 1, derived from centipede Scolopendra subspinipes mutilans and its antifungal mechanism.
RECORD: Rec_0302744 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida tropicalis
10.0 ± 8.7 μM
MIC
RECORD: Rec_0373129 VERIFIED: YES
Provenance & Taxonomy
Scolopendra subspinipes mutilans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Trichosporon beigelii KCTC 7707
20.0±17.3 μM
MIC
PMID25209888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25209888/
RECORD: Rec_0396640 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Trichosporon beigelii KCTC 7707
20±17.3 μM
MIC
PMID25209888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25209888/
RECORD: Rec_0422295 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecium ATCC 19434
10±8.7 μM
MIC
PMID25209888 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25209888/
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