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MYP_032801
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Basic Information
HC(1 12)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C87H141N33O21
Standard
Sequence
GWWRRTVDKVRNAGRK
Physicochemical Analysis
1985.26 Da
12.00
4.76
4.55
0.2974
-1.62
0.77
-0.59
40.59
42.50
0.1250
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
931.66
-9.24
36.0
26.0
66.0
141.0
4.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020529 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
100 μM
MIC
PMID31802582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31802582/
RECORD: Rec_0120218 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
0 %
Hemolysis
PaperPubMed PMID: 31802582 PMID31802582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31802582/
RECORD: Rec_0131061 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
25-200 μM
Hemolysis
PMID31802582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31802582/
RECORD: Rec_0254004 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A2058
200 μM
IC50
PaperPubMed PMID: 31802582 PMID31802582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31802582/
RECORD: Rec_0301910 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
MRC-5
200 μM
IC50
PaperPubMed PMID: 31802582 PMID31802582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31802582/
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