Peptide Database

Peptide NamePreprohepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length89 amino acids

Chemical FormulaC422H690N124O132S9

DescriptionStandard

        MKLISAIVLIVLLSVWTRASSSVPLSETEDQDRQQHLSSVNDQQTAVSTEAHGPLSSLLLREKRQSHFPICLYCCNCCKNKGCGYCCRT
    

Molecular Weight9901.33 Da

Isoelectric Point (pI)8.16

Net Charge (pH 7.0)1.69

Net Charge (pH 7.4) 1.19

Charge Density (pH 7.0) 0.0190

GRAVY Index-0.11

Hydrophobic Moment 0.47

Boman Index-0.02

Instability Index47.02

Aliphatic Index 89.78

Aromaticity 0.0449

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4146.44

LogP -49.12

H-bond Donors 153.0

H-bond Acceptors 146.0

Rotatable Bonds 330.0

Heavy Atoms 687.0

Ring Count 11.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0240616 VERIFIED: NO

Provenance & Taxonomy

OrganismAcipenser baerii [Bacterium]

FamilyHepcidin family

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence