Peptide Database

Peptide NameCecropin DH

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length32 amino acids

Chemical FormulaC167H288N48O39

DescriptionStandard

        KWKIFKKIEKVGRNIRNGIIKAVAVLGEAKAL
    

Molecular Weight3592.37 Da

Isoelectric Point (pI)10.73

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.54

Charge Density (pH 7.0) 0.2112

GRAVY Index0.01

Hydrophobic Moment 0.93

Boman Index-0.01

Instability Index17.19

Aliphatic Index 125.00

Aromaticity 0.0625

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1447.93

LogP -8.43

H-bond Donors 51.0

H-bond Acceptors 46.0

Rotatable Bonds 130.0

Heavy Atoms 254.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0294733 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyCecropin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMicrococcus luteus NCIMB 8166

Activity1.56 μM

MethodMIC

RECORD: Rec_0321774 VERIFIED: YES