Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length676 amino acids

Chemical FormulaC3352H5038N862O1040S23

DescriptionStandard

        MKQNMRKRSPLAVLLALCLAMQLCVPAAMASNRLMRAGDAAIAQIEEEEGFRAEKYSSGGKWYIGYGTECGAEDYPEGITREEAELLLMSKVEAYEAKLNDFFDRYDVTPTQGQFDALICFSYNFGTGWMSGTSDLVKIARGEKDATRLEVAHAFGEWCHSGGQAQAGLADRRLQEAAIYLDDSTRAAENEFAYLIINMESGTSYETDFAVYEIGKTYGNFPKAEKLGYGFAGFQTSDGKTITENSIVNGNAVVTAQWTATSYTGKTYTDVNKSDWFYNYVMELSEQGIVGGNGDGTFAPNRPTSTGEMLKLVLLSTGHKEQKPSTAHWASGYATYAYSMGFAAQNYSDYQLDNGISRLDVARFAAKALGYGASNTTSPFADVNDGYVTALYEAGVFIGTKVGDLTYFYPNSSITRAEVATIVYRIYQLSSLDQKQKIYYKDYTLDVLEGVPTNTYNQSAFVKNGSIMAYNDPSVRTRVGIDVSQYQGDVDWNAVARTDVDFVIARVGGRGYTVGAIYDDTKFDEYADGAARAGLQVGAYFFSQAVSVAEAQEEAYHVLDKLRGHEITGPVVFDWEVIGKREARTYGIETGVLCAAANAFCKIIKDAGYDPMIYITDYAGYVKYDLSEVMDYPLWYARYDVDAPSFYYDFAMWQYSSKGSVDGIKGNVDMDIWFIK
    

Molecular Weight74788.50 Da

Isoelectric Point (pI)4.70

Net Charge (pH 7.0)-28.96

Net Charge (pH 7.4) -29.81

Charge Density (pH 7.0) -0.0428

GRAVY Index-0.27

Hydrophobic Moment 0.77

Boman Index0.06

Instability Index24.18

Aliphatic Index 72.51

Aromaticity 0.1361

Extinction Coeff. Reduced 137980.00

Extinction Coeff. Oxidized 138355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0325798 VERIFIED: NO

Provenance & Taxonomy

OrganismRuminococcaceae bacterium TF06-43 [Bacterium]

FamilyLysozyme

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence