Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length159 amino acids

Chemical FormulaC782H1272N218O233S5

DescriptionStandard

        METQRASLSLGRWSLWLLLLGLALPSASAQALSYREAVLRAVDQLNEKSSEANLYRLLELDPPPKEDDENPNIPKPVSFRVKETVCPRTSQQSPEQCDFKENGLLKECVGTVTLDQVGSNFDITCAVPQSVGGLRSLGRKILRAWKKYGPIIVPIIRIG
    

Molecular Weight17616.11 Da

Isoelectric Point (pI)8.37

Net Charge (pH 7.0)1.49

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0094

GRAVY Index-0.24

Hydrophobic Moment 0.95

Boman Index-0.02

Instability Index44.68

Aliphatic Index 99.94

Aromaticity 0.0566

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21220.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7258.04

LogP -71.15

H-bond Donors 252.0

H-bond Acceptors 240.0

Rotatable Bonds 584.0

Heavy Atoms 1238.0

Ring Count 24.0

Amide Bonds 172.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141281 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyCathelicidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0250050 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

Familycathelicidin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0261852 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]; Bos taurus [Animal]

FamilyCathelicidin

Tax ID9915; 9913

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0268671 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

Familycathelicidin

Tax ID9913

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0338358 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyCathelicidin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-MRSA Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus