Peptide Database

Peptide NameUnnamed

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC47H52N8O9

DescriptionStandard

        YPFGFWG
    

Molecular Weight872.96 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0344

GRAVY Index0.14

Hydrophobic Moment 0.09

Boman Index0.65

Instability Index38.90

Aliphatic Index 0.00

Aromaticity 0.5714

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 265.15

LogP 1.23

H-bond Donors 9.0

H-bond Acceptors 9.0

Rotatable Bonds 20.0

Heavy Atoms 64.0

Ring Count 6.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0189049 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

RECORD: Rec_0350041 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Opioid

Targetmu opioid receptor

Activity0.09 μM

MethodIC50

PaperDooley C.T., Kaplan R.A., Chung N.N., Schiller P.W., Bidlack J.M., Houghten R.A.. Six highly active mu-selective opioid peptides identified from two synthetic combinatorial libraries. Peptide Research, 8, 3, 124-137(1995). PMID7670227 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7670227/