Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition

Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC206H359N57O56

DescriptionStandard

        KIEEIESKQKKIENEIARIKKLLQLTVWGIKQLQARIL
    

Molecular Weight4530.40 Da

Isoelectric Point (pI)9.87

Net Charge (pH 7.0)3.77

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.0991

GRAVY Index-0.42

Hydrophobic Moment 0.66

Boman Index-0.13

Instability Index86.74

Aliphatic Index 136.05

Aromaticity 0.0263

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1904.16

LogP -12.00

H-bond Donors 65.0

H-bond Acceptors 60.0

Rotatable Bonds 169.0

Heavy Atoms 319.0

Ring Count 2.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0039390 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiviral

TargetHIV-1[IC90 I = 1.4+-0.3 microM]

RECORD: Rec_0183414 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0364727 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1:inhibition of cell-cell fusion between 293T cells and HOS-CD4/fusion cells

Activity1.4±0.3 μM

MethodIC50

RECORD: Rec_0414946 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antiviral Anti-HIV-1 Fusion inhibition

TargetHIV-1 | 293T cells; HOS-CD4/fusion cells

Activity1.4±0.3 μM

MethodIC50

Half-LifeMammalian: 1.3 h; Yeast: 3 min; E. coli: 2 min