Peptide Database

Peptide NameLacticin Z

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC269H424N68O66S

DescriptionStandard

        MAGFLKVVQILAKYGSKAVQWAWANKGKILDWINAGQAIDWVVEKIKQILG
    

Molecular Weight5698.72 Da

Isoelectric Point (pI)9.78

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.27

Charge Density (pH 7.0) 0.0686

GRAVY Index0.27

Hydrophobic Moment 0.62

Boman Index0.23

Instability Index11.95

Aliphatic Index 118.63

Aromaticity 0.1176

Extinction Coeff. Reduced 23490.00

Extinction Coeff. Oxidized 23490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2174.52

LogP -10.96

H-bond Donors 74.0

H-bond Acceptors 71.0

Rotatable Bonds 193.0

Heavy Atoms 404.0

Ring Count 10.0

Amide Bonds 56.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0028455 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus lactis [Bacterium]

FamilyBacteriocin

Tax ID1358

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsAPD analysis reveals that the sequence of this peptide shows 90.6% similarity to lacticin Q. Chemical modification: N-terminal Met is formylated. leaderless

Bio-Activity Profile

Function

Antimicrobial

TargetBacillus spp. and Lactobacillus spp, and L. lactis QU 5

Activity0.20600000000000002 μM

MethodMIC