MYP_032655
Phakellistatin 15
Anticancer
Anticancer
▸
Cytotoxic anticancer activity
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Cytotoxic
Antimicrobial
Toxicity / Safety
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Blood cell toxicity
▸
Hemolysis
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Hemolytic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
▸
General toxin
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Cytotoxic
Venom / Toxin
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General toxin
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Toxin
Standard
8 amino acids
C48H73N9O10
Standard
PWIPLTPL
936.15 Da
5.96
-0.04
-0.10
-0.0052
0.71
0.08
0.58
1.55
146.25
0.1250
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
271.47
1.47
9.0
10.0
22.0
67.0
5.0
7.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0026256
VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Toxin
Cytotoxic
Anticancer
Human hepatoma BEL-7404 cell line, BEL-7404 cell line
0.01 μg/mL
ED50
RECORD: Rec_0105681
VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Cytotoxic
RECORD: Rec_0346417
VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0350681
VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Hemolytic
RECORD: Rec_0369611
VERIFIED: YES
Provenance & Taxonomy
Phakellia fusca [Animal]
Phakellistatin
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Anticancer
Tumor cells: P388
8.5 μM
IC50