Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1257H1976N328O353S10

DescriptionStandard

        MLPEPGACGKSTLLPSSCCDCLLRGPLGPDPAVAPSPGSDTPFSPAPFLLPDEGDHMLLLGLSEFSANSAAFVYFTAGSLRKNFRDDMIPKRSPIRLNTGSVGVFFPEVRKLYPDMPMELHLSARKQPLLTCRPDSLALALFGTAEAFVVLPNATLASAFLLDLVSAGQGPGHPGSLSPRGPGILLPLGSGSSPLTSAPFVSPEKLKKGFPLPSIYNLSLVNPHVKINQVGLSHGLGSTSYPVPALGTPKPVARVPFQTGWGHL
    

Molecular Weight27651.77 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)2.99

Net Charge (pH 7.4) 2.36

Charge Density (pH 7.0) 0.0113

GRAVY Index0.11

Hydrophobic Moment 0.52

Boman Index0.18

Instability Index47.99

Aliphatic Index 90.53

Aromaticity 0.0720

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249555 VERIFIED: NO

Provenance & Taxonomy

OrganismChelonoidis abingdonii (Abingdon island giant tortoise) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria