Peptide Database

Peptide NameCangitoxin

Function Ontology

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length48 amino acids

Chemical FormulaC209H323N65O64S6

DescriptionStandard

        GVACRCDSDGPTVRGNSLSGTLWLTGGCPSGWHNCRGSGPFIGYCCKK
    

Molecular Weight4962.59 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0581

GRAVY Index-0.26

Hydrophobic Moment 0.34

Boman Index0.04

Instability Index50.31

Aliphatic Index 46.67

Aromaticity 0.0833

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2045.50

LogP -28.43

H-bond Donors 79.0

H-bond Acceptors 74.0

Rotatable Bonds 154.0

Heavy Atoms 344.0

Ring Count 10.0

Amide Bonds 49.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0175614 VERIFIED: NO

Provenance & Taxonomy

OrganismBunodosoma cangicium [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-45; 6-35; 28-46

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0433380 VERIFIED: YES

Provenance & Taxonomy

OrganismBunodosoma cangicium [Animal]

Structure & Mods

Configlinear disulfide-stabilized peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide4-45; 6-35; 28-46

Bio-Activity Profile

Function

Toxin Epileptogenic Neurotoxic

TargetRattus norvegicus hippocampus

Activity8-12 h

Methodintrahippocampal injection; behavioral and EEG seizure monitoring