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MYP_032625
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Basic Information
Casein beta [136-140]
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Standard
5 amino acids
C28H49N5O6
Standard
Sequence
PLPLL
Physicochemical Analysis
551.72 Da
5.96
-0.04
-0.10
-0.0083
1.64
0.28
0.68
46.52
234.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
156.94
1.41
5.0
6.0
14.0
39.0
2.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000919 VERIFIED: YES
Provenance & Taxonomy
Bos grunniens [Animal]
Casein-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
250±10 μg/mL
IC50
RECORD: Rec_0004176 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0110143 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Mammalia [Animal]
9913; 40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperIsolation and characterization of peptides with antihypertensive activity in foodstuffs PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0150217 VERIFIED: NO
Provenance & Taxonomy
Bos grunniens [Animal]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperThe potential role of milk-derived peptides in cardiovascular disease. PMID21779574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21779574/
RECORD: Rec_0315995 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
0.53
IC50
PaperMao X.-Y., Ni J.-R., Sun W.-L., Hao P.-P., Fan L.. Value-added utilization of yak milk casein for the production of angiotensin-I-converting enzyme inhibitory peptides. Food Chem., 2007, 103:1282-1287.
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