Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC343H543N87O95S9

DescriptionStandard

        MKTSLFLFAALFFLTPAKNAFFDEKCYQLKGRCMDHCKKNEELVALCQKSLKCCLTLQSCGKTKFDD
    

Molecular Weight7694.09 Da

Isoelectric Point (pI)8.73

Net Charge (pH 7.0)3.52

Net Charge (pH 7.4) 3.13

Charge Density (pH 7.0) 0.0526

GRAVY Index-0.08

Hydrophobic Moment 0.46

Boman Index-0.01

Instability Index39.11

Aliphatic Index 70.00

Aromaticity 0.1194

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2964.30

LogP -24.90

H-bond Donors 108.0

H-bond Acceptors 109.0

Rotatable Bonds 265.0

Heavy Atoms 534.0

Ring Count 10.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157933 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence