MYP_032621
Lantibiotic peptide, Nisin Z
Antimicrobial
Antimicrobial
▸
Antibacterial
not Standard
34 amino acids
-
contains X representing unresolved or non-standard residue
IXXIXLXXPGXKXGALMGXNMKXAXXNXSIHVXK
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0273527
VERIFIED: NO
Provenance & Taxonomy
Lactococcus lactis,Streptococcus lactis [Bacterium]
Structure & Mods
thioether-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
S3-C7: lanthionine; T8-C11, T13-C19, T23-C26 and T25-C28: beta-methyllanthionine; T2: 2, 3-didehydrobutyrine; S5 and S33: 2, 3-didehydroalanine
Bio-Activity Profile
Antimicrobial
Antibacterial
RECORD: Rec_0433378
VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis,Streptococcus lactis [Bacterium]
Structure & Mods
thioether-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
S3-C7: lanthionine; T8-C11, T13-C19, T23-C26 and T25-C28: beta-methyllanthionine; T2: 2, 3-didehydrobutyrine; S5 and S33: 2, 3-didehydroalanine
Bio-Activity Profile
Antimicrobial
Antibacterial
Staphylococcus aureus
~2 log CFU reduction
CFU reduction assay (100 mM NaCl)
RECORD: Rec_0433379
VERIFIED: YES
Provenance & Taxonomy
Lactococcus lactis,Streptococcus lactis [Bacterium]
Structure & Mods
thioether-constrained peptide [Cyclic]
noncanonical stereochemical modification [Modified]
S3-C7: lanthionine; T8-C11, T13-C19, T23-C26 and T25-C28: beta-methyllanthionine; T2: 2, 3-didehydrobutyrine; S5 and S33: 2, 3-didehydroalanine
Bio-Activity Profile
Antimicrobial
Antibacterial
Escherichia coli
CFU reduction and membrane permeabilization assay