Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC722H1135N183O220S12

DescriptionStandard

        MNLLMLTFVICALLTQVTKGSFAAQKCWKNNIGYCRRRCLDTERYILLCGNKLSCCISIIISYEYTQRPAFPVIHLEDITFDYSYMDFFTGSPVSRLNDLVTFETTSSGEAMTLETNTFETTMPPPKATTSKTTVPSSPTALTNN
    

Molecular Weight16283.61 Da

Isoelectric Point (pI)6.54

Net Charge (pH 7.0)-0.47

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0032

GRAVY Index-0.01

Hydrophobic Moment 0.60

Boman Index0.08

Instability Index52.64

Aliphatic Index 78.69

Aromaticity 0.1034

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14815.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6465.95

LogP -67.37

H-bond Donors 233.0

H-bond Acceptors 233.0

Rotatable Bonds 524.0

Heavy Atoms 1137.0

Ring Count 25.0

Amide Bonds 155.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0231487 VERIFIED: NO

Provenance & Taxonomy

OrganismSaimiri boliviensis boliviensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence