‹ ›
MYP_032596
← PREVIOUS NEXT → BACK
Basic Information
Pexiganan acetate
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Immunology ▸ Inflammation modulation ▸ Anti-inflammatory
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Wound healing/Regeneration ▸ Wound healing
Standard
22 amino acids
C122H209N31O23
Standard
Sequence
GIGKFLKKAKKFGKAFVKILKK
Physicochemical Analysis
2478.16 Da
10.90
8.75
8.53
0.3978
-0.16
0.79
-0.06
-6.16
93.18
0.1364
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
908.60
-2.76
32.0
32.0
94.0
176.0
3.0
21.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0373079 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pexiganan acetate [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Anti-inflammatory Wound healing
P. asaccharolyticus 3 strains
4-8 μg/mL
MIC
PaperPotential therapeutic applications of magainins and other antimicrobial agents of animal origin.
RECORD: Rec_0375012 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Melittin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
multidrug-resistant Pseudomonas aeruginosa CCARM 2161
PMID25445605 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25445605/
RECORD: Rec_0377384 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pexiganan acetate [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Anti-inflammatory Wound healing
Enterococcus faecalis 30 strains
>256 μg/mL
MIC
PaperPotential therapeutic applications of magainins and other antimicrobial agents of animal origin.
RECORD: Rec_0377479 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Pexiganan acetate [Synthetic]
Magainin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Anti-inflammatory Wound healing
Enterobacter cloacae 25 strains
1-128 μg/mL
MIC
PaperPotential therapeutic applications of magainins and other antimicrobial agents of animal origin.
RECORD: Rec_0381519 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Magainin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
OVRCAR-3
13
LC50
PMID24587350 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24587350/
FIRST PREV 1 ... 17 18 19 20 21 22 NEXT LAST
Showing 5 records on this page · Page 19 of 22