‹ ›
MYP_032593
← PREVIOUS NEXT → BACK
Basic Information
Interferon gamma-1b
Anticancer
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Anti-HIV
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Immunomodulation ▸ Immunosuppressive
Therapeutic / Biomedical activity ▸ Enzyme replacement therapy
Standard
146 amino acids
C761H1206N214O225S6
Standard
Sequence
CYCQDPYVKEAENLKKYFNAGHSDVADNGTLFLGILKNWKEESDRKIMQSQIVSFYFKLFKNFKDDQSIQKSVETIKEDMNVKFFNSNKKKRDDFEKLTNYSVTDLNVQRKAIHELIQVMAELSPAAKTGKRKRSQMLFRGRRASQ
Physicochemical Analysis
17145.41 Da
9.54
8.93
8.53
0.0611
-0.82
0.62
-0.21
32.92
66.78
0.1096
12950.00
13075.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
7306.23
-73.07
253.0
242.0
603.0
1206.0
21.0
164.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0123696 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]; Escherichia coli [Bacterium]
Interferon
9606;562
Structure & Mods
linear multidomain protein biologic [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunomodulatory Immunosuppressive Antiviral
PaperPubMed-linked source references: PMID:25470089; PMID:25335475; PMID:24576196; PMID:19570573; PMID:18644457; PMID:18314182; PMID:17128525; PMID:16637863; PMID:16611657 PMID25470089;25335475;24576196;19570573;18644457;18314182;17128525;16637863;16611657 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25470089/ PatentUS6936695
RECORD: Rec_0216650 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Interferon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Anti-HCV Immunomodulatory
Hepatitis C virus
PMID16375755 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16375755/
RECORD: Rec_0259563 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]; Escherichia coli [Bacterium]
Immunoglobulin
9606; 562
Structure & Mods
single-chain therapeutic peptide/protein [Linear]
canonical L-amino-acid peptide [L]
Phosphorylation
Bio-Activity Profile
Antiviral Anticancer Immunomodulatory Enzyme replacement
Evidence URLhttps://patents.google.com/patent/US6936695/en PatentUS6936695
RECORD: Rec_0298268 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Interferon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Anti-HIV Immunomodulatory
Human immunodeficiency virus 1
PMID14525967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14525967/