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MYP_032579
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Basic Information
Angiotensin I-converting enzyme inhibitor EP
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
2 amino acids
C10H16N2O5
Standard
Sequence
EP
Physicochemical Analysis
244.24 Da
4.05
-1.16
-1.33
-0.5816
-2.55
0.39
-0.31
101.30
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
120.93
-0.75
3.0
4.0
5.0
17.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0305639 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
2.92 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0318571 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
human dipeptidyl peptidase IV
PaperHikida A., Ito K., Motoyama T., Kato R., Kawarasaki Y.. Systematic analysis of a dipeptide library for inhibitor development using human dipeptidyl peptidase IV produced by a Saccharomyces cerevisiae expression system. Biochemical and Biophysical Research Communications 430, 1217-1222.
RECORD: Rec_0359716 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory Insulin-secretion stimulatory
ACE
1200 μM
IC50
PaperAngiotensin I-converting enzyme inhibitory activity and insulin secretion stimulative activity of fermented fish sauce PMID16233562 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16233562/
RECORD: Rec_0371876 VERIFIED: YES
Provenance & Taxonomy
Amaranthus hypochondriacus [Plant]
ACE inhibitory peptide
28502
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory Antihypertensive
PMID19443002 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19443002/
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