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MYP_032577
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Basic Information
Tachystain C
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antimicrobial ▸ Antifungal ▸ Fungicidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
41 amino acids
C214H324N68O55S6
Standard
Sequence
DYDWSLRGPPKCATYGQKCRTWSPPNCCWNLRCKAFRCRPR
Physicochemical Analysis
4921.67 Da
9.55
6.70
6.40
0.1634
-1.08
0.48
-0.33
48.17
23.90
0.1463
19480.00
19855.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2005.45
-20.72
78.0
68.0
149.0
343.0
14.0
43.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0037894 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Sheep erythrocytes
5 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10473569/ PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0037998 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Sheep erythrocytes
10 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/10473569/ PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0068112 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
0.8 μg/mL
IC50
PaperPubMed PMID: 10473569 PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0087042 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 4.9%, T 26.8%, C 68.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Toxic Antimicrobial Antifungal Hemolytic
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0087813 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Tachystatin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
0.9 μg/mL
IC50
PMID10473569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
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