Peptide Database

Peptide NameTetraF2W-KK

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC68H88N14O9

DescriptionStandard

        WWWLKKIW
    

Molecular Weight1245.51 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.2198

GRAVY Index-0.39

Hydrophobic Moment 0.48

Boman Index0.34

Instability Index2.95

Aliphatic Index 97.50

Aromaticity 0.5000

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 382.22

LogP 5.04

H-bond Donors 15.0

H-bond Acceptors 11.0

Rotatable Bonds 35.0

Heavy Atoms 91.0

Ring Count 8.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398480 VERIFIED: YES

Provenance & Taxonomy

OrganismSynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Other ModsAPD analysis reveals that this sequence is poorly similar (87.5%) to TetraF2W-RK . W: 50%. Chemical modification: C-terminal amidation

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetBacillus subtilis 168

Activity6.2 μM

MethodMIC

RECORD: Rec_0423517 VERIFIED: NO