MYP_032560
Basic Information
Toxin HmTx1
Annotation / Sequence feature Nuclear export signal
Anticancer Cytotoxic anticancer activity Cytotoxic
Membrane / Ion-channel modulation Ion channel inhibition
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
Venom / Toxin General toxin huwentoxin-1 family
Venom / Toxin General toxin Toxic
Venom / Toxin General toxin Toxin
Venom / Toxin Toxin
Standard
35 amino acids
C170H245N47O54S6
Standard
Sequence
ECRYLFGGCSSTSDCCKHLSCRSDWKYCAWDGTFS
Physicochemical Analysis
4003.44 Da
6.78
-0.14
-0.45
-0.0039
-0.45
0.36
-0.08
52.11
25.14
0.1714
13980.00
14355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1640.32
-19.95
67.0
61.0
126.0
277.0
9.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0093983 VERIFIED: NO
Provenance & Taxonomy
Heteroscodra maculata [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
2-16; 9-21; 15-28
Bio-Activity Profile
Toxin
Kv2, Kv4
RECORD: Rec_0313891 VERIFIED: YES
Provenance & Taxonomy
Heteroscodra maculata [Animal]
huwentoxin-1 family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
2-16; 9-21; 15-28
Bio-Activity Profile
Toxin Venom huwentoxin-1 family Ion channel inhibitor Pathogenesis-associated
RECORD: Rec_0336207 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 8.6%, E 22.9%, T 34.3%, C 34.3% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Toxic Cytotoxic