Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC384H624N112O99S10

DescriptionStandard

        MTRVVMKICDLCFWAGRQEVRSGLNRYIKSLFSTCWQLKGVCKKTCARKEEYHIFCNAGLLCCVDKKHLPIRTGK
    

Molecular Weight8714.40 Da

Isoelectric Point (pI)9.53

Net Charge (pH 7.0)9.60

Net Charge (pH 7.4) 9.14

Charge Density (pH 7.0) 0.1279

GRAVY Index-0.13

Hydrophobic Moment 0.67

Boman Index-0.07

Instability Index26.68

Aliphatic Index 80.53

Aromaticity 0.0933

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3443.38

LogP -29.20

H-bond Donors 132.0

H-bond Acceptors 121.0

Rotatable Bonds 297.0

Heavy Atoms 605.0

Ring Count 12.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0421006 VERIFIED: NO

Provenance & Taxonomy

OrganismRhinolophus ferrumequinum [Animal]

FamilyDefensin

Tax ID59479

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal