Peptide Database

Peptide NameUnnamed

Function Ontology

Anticancer ▸ Tumor T-cell antigen

Immunology ▸ Epitope/vaccine antigen ▸ T-cell epitope

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC44H71N11O13

DescriptionStandard

        FLTGNQLAV
    

Molecular Weight962.10 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0267

GRAVY Index0.92

Hydrophobic Moment 0.18

Boman Index0.42

Instability Index-18.36

Aliphatic Index 130.00

Aromaticity 0.1111

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 402.53

LogP -3.56

H-bond Donors 13.0

H-bond Acceptors 13.0

Rotatable Bonds 30.0

Heavy Atoms 68.0

Ring Count 1.0

Amide Bonds 10.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0326765 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Immunomodulatory Tumor T-cell antigen T-cell epitope

Target-

RECORD: Rec_0433369 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Family5T4-derived HLA-A2 epitope

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

T-cell epitope Immunogenic Tumor T-cell antigen Immunomodulatory

TargetT2 cells; HLA-A2-restricted CD8+ T cells

Activity10-100 pM

Method4-hour cytotoxicity assay (half-maximal target lysis)