Peptide Database

Peptide NameSLAY-screened peptide P663

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC90H135N21O16S

DescriptionStandard

        MIHFWVLPGRLLFIG
    

Molecular Weight1799.23 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)0.59

Net Charge (pH 7.4) 0.32

Charge Density (pH 7.0) 0.0392

GRAVY Index1.41

Hydrophobic Moment 0.36

Boman Index0.60

Instability Index17.83

Aliphatic Index 149.33

Aromaticity 0.2000

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 568.30

LogP 2.03

H-bond Donors 20.0

H-bond Acceptors 19.0

Rotatable Bonds 54.0

Heavy Atoms 128.0

Ring Count 6.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293755 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/