Peptide Database

Peptide NameDNA dC->dU-editing enzyme APOBEC-3G

Function Ontology

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral budding inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor

Standard StatusStandard

Sequence Length384 amino acids

Chemical FormulaC2093H3108N574O563S24

DescriptionStandard

        MKPHFRNPVERMYQDTFSDNFYNRPILSHRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYSKLKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDVATFLAEDPKVTLTIFVARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPKYYILLHIMLGEILRHSMDPPTFTSNFNNELWVRGRHETYLCYEVERLHNDTWVLLNQRRGFLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLHQDYRVTCFTSWSPCFSCAQEMAKFISNNKHVSLCIFAARIYDDQGRCQEGLRTLAKAGAKISIMTYSEFKHCWDTFVDHQGCPFQPWDGLEEHSQALSGRLRAILQNQGN
    

Molecular Weight46088.14 Da

Isoelectric Point (pI)8.62

Net Charge (pH 7.0)7.96

Net Charge (pH 7.4) 6.51

Charge Density (pH 7.0) 0.0207

GRAVY Index-0.57

Hydrophobic Moment 0.71

Boman Index-0.07

Instability Index36.64

Aliphatic Index 66.28

Aromaticity 0.1536

Extinction Coeff. Reduced 105310.00

Extinction Coeff. Oxidized 106185.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0163973 VERIFIED: YES

Provenance & Taxonomy

OrganismPan troglodytes [Animal]

FamilyAPOBEC

Tax ID9598

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsPhosphorylation Thr32, Thr218

Bio-Activity Profile

Function

Antiviral Replication inhibitor Anti-SFV

TargetSimian foamy virus (SFV)

RECORD: Rec_0362607 VERIFIED: YES